王志强
发布人:陈建  发布时间:2022-04-27   浏览次数:47

 

个人简介:

王志强,男,19769月出生,医学博士,主任医师/副教授、硕士生导师,中华医学会神经病学分会神经肌肉病学组委员,福建省医学会神经病学分会青年委员会副主任委员,福建省医学会医学遗传学分会员,福建省遗传学会常务理事。擅长于肌肉疾病、周围神经病及神经遗传病等的诊治,对神经肌肉病理学及分子诊断积累了丰富经验,重点研究肌营养不良症、代谢性肌病、炎症性肌病等的诊治与发病机制,主持3项国家自然科学基金及多项省厅课题,近年以通讯作者(或第一作者)在Lancet Reg Health West Pac, BRAIN, J  Med Genet, Eur J NeurolEur J Hum Genet, Clin Genet, J Mol Med等杂志发表SCI论著10余篇。

科研成果:

20221月获得“福建省高层次人才C类”荣誉称号

代表性成果:为共同第一作者,*为通信作者

1.Wang Z, Qiu L, Lin M,  Chen L, Zheng F, Lin L, Lin F, Ye Z, Lin X, He J, Wang L, Lin X, He Q, Chen W, Lin Y*, Fu Y*, Wang N*. Prevalence and disease progression of genetically-confirmed facioscapulohumeral muscular dystrophy type 1 (FSHD1) in China between 2001 and 2020: a nationwide population-based  study. Lancet Reg Health West Pac, 2022, 18: 100323.

2.Qiu L, Ye Z, Lin L, Wang L, Lin X, He J, Lin F, Xu G, Cai N, Jin M, Chen H, Lin M, Wang N*, Wang Z*. Clinical and genetic features of somatic  mosaicism in facioscapulohumeral dystrophy. J Med Genet. 2020: jmedgenet-2019-106638.

3.Jin M, Li JJ, Xu GR, Wang N*, Wang Z*. Cryptic exon activation  causes dystrophinopathy in two Chinese families. Eur J Hum Genet. 2020; 28(7):947-955.

4.He JJ, Lin XD, Lin F, Xu GR, Xu LQ, Hu W, Wang DN, Lin HX, Lin MT, Wang N, Wang Z*. Clinical and genetic features of patients with facial-sparing facioscapulohumeral muscular dystrophy. Eur J Neurol. 2018; 25(2): 356-364.

5.Lin F, He JJ, Lin XD, Wang DN, Lin HX, Liu XY, Lin MT, Wang N, Wang Z*. A large cohort study confirming that specific haplotype 4A161PAS is exclusively associated with the Chinese FSHD1. Clin Genet. 2016 Dec; 90(6): 558-559.

6.Wang Z, Chen XJ, Murong SX, Wang N, Wu ZY*. Molecular analysis of 51 unrelated pedigrees with late-onset multiple acyl-CoA dehydrogenation deficiency  (MADD) in southern China confirmed the most common ETFDH mutation and high  carrier frequency of c.250G>A. J Mol Med (Berl). 2011; 89(6): 569-76.

7.Wang Z, Wang N, van der Maarel S, Murong SX, Wu ZY*. Distinguishing the 4qA and 4qB  variants is essential for the diagnosis of facioscapulohumeral muscular dystrophy in the Chinese population. Eur J Hum Genet. 2011; 19(1): 64-9.