个人简介：

王志强，医学博士，福建医科大学附属第一医院神经内科主任医师、教授、博士生导师，中华医学会神经病学分会肌病学组委员，中国罕见病联盟DMD/BMD学组副主任，福建省医学会医学遗传学分会委员，福建省遗传学会理事，福建省高层次人才。擅长于神经肌肉疾病、周围神经病及神经遗传病等的诊治，对神经肌肉病理学及分子诊断积累了丰富经验，重点研究肌营养不良症、代谢性肌病、炎症性肌病等的诊治与发病机制，主持3项国家自然科学基金，近三年来以通讯作者（或第一作者）在Neurol, Ann Neurol, the Lancet regional health, Acta Neuropathol, Brain等杂志发表SCI论著20余篇。

科研成果：

2022年1月获得“福建省高层次人才C类”荣誉称号

代表性成果：（†为共同第一作者，*为通信作者）

1. Zheng FZ†, Qiu LL†, Chen L, Zheng Y, Lin XD, He JJ, Lin X, He QF, Lin YH, Lin L, Wang LL, Lin F, Yang K, Lin MT, Lin Y, Fu Y, Wang N, Wang ZQ*. Association of 4qA-Specific Distal D4Z4 Hypomethylation With Disease Severity and Progression in Facioscapulohumeral Muscular Dystrophy. Neurology, 2023, 101(3):e225-e237. 

2. Zheng FZ†, Qiu LL†, Chen L, Zheng Y, He QF, Lin X, Lin MT, Lin Y, Fu Y, Wang N, Wang ZQ*. An epigenetic basis for genetic anticipation in facioscapulohumeral muscular dystrophy type 1. Brain, 2023, 146(12): e107-e110. 

3. Wang ZQ†, Qiu LL†,, Lin MT†, Chen L, Zheng FZ, Lin L, Lin F, Ye ZX, Lin XD, He JJ, Wang LL, Lin X, He QF, Chen WJ, Lin Y*, Fu Y*, Wang N*. Prevalence and disease progression of genetically-confirmed facioscapulohumeral muscular dystrophy type 1 (FSHD1) in China between 2001 and 2020: a nationwide population-based study. The Lancet Regional Health-Western Pacific, 2022, 18: 100323. 

4. Qiu LL†, Chen L, Zheng FZ, Lin MT, Lin Y, Fu Y, Wang N*; Wang ZQ*. Wheelchair use in genetically confirmed FSHD1 from a large cohort study in Chinese population. Brain, 2022, 145(6): e51-e54. 

5. Zeng YH†, Yang K†, Du GQ, Chen YK, Cao CY, Qiu YS, He J, Lv HD, Qu QQ, Chen JN,  Xu GR, Chen L, Zheng FZ, Zhao M, Lin MT, Chen WJ, Hu J, Wang ZQ*; Wang N*. GGC Repeat Expansion of RILPL1 is Associated with Oculopharyngodistal Myopathy. Annals of Neurology, 2022, 92(3): 512-526.

6. Yang K†, Zeng YH†, Qiu YS, Lin F, Chen HZ, Jin M, Chen L, Zheng FZ, Ding YL, Cao CY ; Lin MT, Chen WJ, Wang ZQ*, N Wang*. Expanding the phenotype and genotype spectra of PLIN4-associated myopathy with rimmed ubiquitinpositive autophagic vacuolation. Acta Neuropathologica, 2022, 143(6): 733-735. 

7. Qiu LL†, Ye ZX, Lin L, Wang LL, Lin XD, He JJ, Lin F, Xu GR, Cai NQ, Jin M, Chen HZ, Lin MT, Wang N*, Wang ZQ*. Clinical and genetic features of somatic mosaicism in facioscapulohumeral dystrophy. J Med Genet, 2020, 57(11):777-785.

8. Lin F†, Yang K, Lin MT, Zheng FZ, Chen L, Ding YL, Ye ZX, Lin X, Wang N, Wang ZQ*. The phenotypic and genotypic features of Chinese patients with oculopharyngeal muscular dystrophy. Ann Clin Transl Neurol, 2023, 10(3):426-439.

9. Lin F†, Yang K, Lin X, Jin M, Chen L, Zheng FZ, Qiu LL, Ye ZX, Chen HZ, Lin MT, Wang N, Wang ZQ*. Clinical features, imaging findings and molecular data of limb-girdle muscular dystrophies in a cohort of Chinese patients. Orphanet J Rare Dis. 2023, 16;18(1):356.

10. Shi Y†, Cao CY, Zeng YH, Ding YL, Chen L, Zheng FZ, Chen XJ, Zhou FG, Yang XF, Li JJ, Xu LQ, Xu GR, Lin MT, Ishiura H, Tsuji S, Wang N, Wang ZQ*, Chen WJ*, Yang K*. CGG repeat expansion in LOC642361/NUTM2B-AS1 typically presents as oculopharyngodistal myopathy. J Genet Genomics. 2024, 51(2):184-196.